Systematic investigation of the homology sequences around the human fusion gene breakpoints in pan-cancer - bioinformatics study for a potential link to MMEJ.

Kim, Pora; Kumar, Himansu; Yang, Chengyuan; Luo, Ruihan; Liu, Jiajia; Zhou, Xiaobo

Kim, Pora; Kumar, Himansu; Yang, Chengyuan; Luo, Ruihan; Liu, Jiajia; Zhou, Xiaobo.

Afiliação

Kim P; School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Kumar H; School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Yang C; School of Public Health Informatics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Luo R; School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Liu J; School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Zhou X; School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.

Brief Bioinform ; 24(5)2023 09 20.

Article em En | MEDLINE | ID: mdl-37635381

Assuntos

Biologia Computacional; Neoplasias; Humanos; Genômica; Neoplasias/genética; Éxons; Instabilidade Genômica

Palavras-chave

DNA damage repair; MMEJ; fusion gene breakpoint; fusion neoantigen; fusionAI; microhomology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biologia Computacional / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Brief Bioinform Assunto da revista: BIOLOGIA / INFORMATICA MEDICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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