Extending the vision of adaptive point-of-care platform trials to improve targeted use of drug therapy regimens: An agile approach in the learning healthcare system toolkit.

Hirsch, Gigi; Velentgas, Priscilla; Curtis, Jeffrey R; Larholt, Kay; Park, Jay J H; Pashos, Chris L; Trinquart, Ludovic

Hirsch, Gigi; Velentgas, Priscilla; Curtis, Jeffrey R; Larholt, Kay; Park, Jay J H; Pashos, Chris L; Trinquart, Ludovic.

Afiliação

Hirsch G; Center for Biomedical System Design & NEWDIGS, Tufts Medical Center, Boston, MA, USA. Electronic address: Gigi.Hirsch@tuftsmedicine.org.
Velentgas P; Merck Epidemiology, Inc., Boston, MA, USA.
Curtis JR; Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; Illumination Health, Hoover, AL, USA.
Larholt K; Center for Biomedical System Design & NEWDIGS, Tufts Medical Center, Boston, MA, USA.
Park JJH; Core Clinical Sciences Inc, Vancouver, BC, Canada; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Pashos CL; Genesis Research, Hoboken, NJ, USA.
Trinquart L; Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, USA; Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, USA.

Contemp Clin Trials ; 133: 107327, 2023 Oct.

Article em En | MEDLINE | ID: mdl-37652359

Palavras-chave

Adaptive point-of-care platform trials; Learning healthcare system; Multi-stakeholder system design; Sequential multiple assignment randomized trial (SMART) design

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Contemp Clin Trials Assunto da revista: MEDICINA / TERAPEUTICA Ano de publicação: 2023 Tipo de documento: Article

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