Prenylated C6-C3 derivatives from the root of Illicium ternstroemioides with antiviral activity.
J Asian Nat Prod Res
; 26(4): 452-464, 2024 Apr.
Article
em En
| MEDLINE
| ID: mdl-37655543
ABSTRACT
Six previously undescribed prenylated C6-C3 derivatives (1-6) were isolated from the root of Illicium ternstroemioides A. C. Smith. Their structures were elucidated based on extensive spectroscopic analyses (UV, IR, 1D and 2D NMR, and HRESIMS). The absolute configurations of 1-3 were determined using electronic circular dichroism (ECD), and Mo2(OAc)4 induced circular dichroism (ICD). Compound 3 exhibited weak activity against Coxsackievirus B3 with an IC50 value of 33.3 µM, and compound 5 exhibited more potent activity against Coxsackievirus B3 with an IC50 value of 6.4 µM.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Illicium
Idioma:
En
Revista:
J Asian Nat Prod Res
Assunto da revista:
BOTANICA
/
QUIMICA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China