Design, synthesis, and evaluation of a mitoxantrone probe (MXP) for biological studies.

Wallin, Savanna; Singh, Sarbjit; Borgstahl, Gloria E O; Natarajan, Amarnath

Wallin, Savanna; Singh, Sarbjit; Borgstahl, Gloria E O; Natarajan, Amarnath.

Afiliação

Wallin S; The Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, United States.
Singh S; The Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, United States.
Borgstahl GEO; The Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, United States. Electronic address: gborgstahl@unmc.edu.
Natarajan A; The Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, United States. Electronic address: anatarajan@unmc.edu.

Bioorg Med Chem Lett ; 94: 129465, 2023 10 01.

Article em En | MEDLINE | ID: mdl-37669721

Assuntos

Mitoxantrona; Humanos; Masculino; DNA Topoisomerases Tipo II; Proteínas de Ligação a DNA; Mitoxantrona/farmacologia; Neoplasias da Próstata/tratamento farmacológico; Proteoma; Proteômica; Sondas Moleculares/química; Sondas Moleculares/farmacologia; Neoplasias da Mama/tratamento farmacológico; Feminino

Palavras-chave

Biotin; DNA repair; Mitoxantrone; Probe; RAD52

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mitoxantrona Limite: Female / Humans / Male Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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