Real-time imaging of drug-induced trapping of cellular topoisomerases and poly(ADP-ribose) polymerase 1 at the single-molecule level.

Sun, Yilun; Chen, Jiji; Pommier, Yves

Sun, Yilun; Chen, Jiji; Pommier, Yves.

Afiliação

Sun Y; Laboratory of Molecular Pharmacology and Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Chen J; Advanced Imaging and Microscopy (AIM) Resource, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, USA.
Pommier Y; Laboratory of Molecular Pharmacology and Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Nucleic Acids Res ; 51(18): e97, 2023 10 13.

Article em En | MEDLINE | ID: mdl-37670571

Assuntos

Inibidores de Poli(ADP-Ribose) Polimerases; Poli(ADP-Ribose) Polimerases; Inibidores de Poli(ADP-Ribose) Polimerases/farmacologia; Poli(ADP-Ribose) Polimerase-1/metabolismo; Poli(ADP-Ribose) Polimerases/metabolismo; Dano ao DNA; Reparo do DNA; Isomerases/genética; DNA Topoisomerases Tipo I/metabolismo; DNA/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Poli(ADP-Ribose) Polimerases / Inibidores de Poli(ADP-Ribose) Polimerases Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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