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Pyrimidine-morpholine hybrids as potent druggable therapeutics for Alzheimer's disease: Synthesis, biochemical and in silico analyses.
Zaib, Sumera; Younas, Muhammad Tayyab; Khan, Imtiaz; Ali, Hafiz Saqib; McAdam, Christopher John; White, Jonathan M; Jaber, Fadi; Awwad, Nasser S; Ibrahium, Hala A.
Afiliação
  • Zaib S; Department of Basic and Applied Chemistry, Faculty of Science and Technology, University of Central Punjab, Lahore 54590, Pakistan. Electronic address: sumera.zaib@ucp.edu.pk.
  • Younas MT; Department of Basic and Applied Chemistry, Faculty of Science and Technology, University of Central Punjab, Lahore 54590, Pakistan.
  • Khan I; Department of Chemistry and Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester MI 7DN, UK. Electronic address: kimtiaz@hotmail.co.uk.
  • Ali HS; Chemistry Research Laboratory, Department of Chemistry and the INEOS Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, UK.
  • McAdam CJ; Department of Chemistry, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand.
  • White JM; School of Chemistry and Bio-21 Institute, University of Melbourne, 3052 Parkville, Australia.
  • Jaber F; Department of Biomedical Engineering, Ajman University, Ajman, United Arab Emirates; Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates.
  • Awwad NS; Department of Chemistry, King Khalid University, P.O. Box 9004, Abha 61413, Saudi Arabia.
  • Ibrahium HA; Biology Department, Faculty of Science, King Khalid University, P.O. Box 9004, Abha 61413, Saudi Arabia.
Bioorg Chem ; 141: 106868, 2023 12.
Article em En | MEDLINE | ID: mdl-37738768
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Colinesterase / Doença de Alzheimer Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Colinesterase / Doença de Alzheimer Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2023 Tipo de documento: Article