Tackling the Root Cause of Surface-Induced Coagulation: Inhibition of FXII Activation to Mitigate Coagulation Propagation and Prevent Clotting.

Witzdam, Lena; Vosberg, Berlind; Große-Berkenbusch, Katharina; Stoppelkamp, Sandra; Wendel, Hans Peter; Rodriguez-Emmenegger, Cesar

Witzdam, Lena; Vosberg, Berlind; Große-Berkenbusch, Katharina; Stoppelkamp, Sandra; Wendel, Hans Peter; Rodriguez-Emmenegger, Cesar.

Afiliação

Witzdam L; Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Carrer de Baldiri Reixac, 10, 12, Barcelona, 08028, Spain.
Vosberg B; DWI-Leibniz Institute for Interactive Materials, Forckenbeckstraße 50, 52074, Aachen, Germany.
Große-Berkenbusch K; Institute of Technical and Macromolecular Chemistry, RWTH Aachen University, Worringerweg 2, 52074, Aachen, Germany.
Stoppelkamp S; DWI-Leibniz Institute for Interactive Materials, Forckenbeckstraße 50, 52074, Aachen, Germany.
Wendel HP; Institute of Technical and Macromolecular Chemistry, RWTH Aachen University, Worringerweg 2, 52074, Aachen, Germany.
Rodriguez-Emmenegger C; Clinic for Thoracic and Cardiovascular Surgery, University Hospital Tuebingen, Calwerstr, 7/1, 72076, Tuebingen, Germany.

Macromol Biosci ; 24(2): e2300321, 2024 Feb.

Article em En | MEDLINE | ID: mdl-37742317

Assuntos

Coagulação Sanguínea; Fator XII; Fator XII/metabolismo; Fator XII/farmacologia; Fator XIIa/metabolismo; Polímeros/farmacologia

Palavras-chave

C1-esterase-inhibitor; FXII activation; hemocompatibility; hemocompatible surface modification; polymer brushes; ß-FXIIa

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Coagulação Sanguínea / Fator XII Idioma: En Revista: Macromol Biosci Assunto da revista: BIOQUIMICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Espanha

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