Delayed-type allergic reaction to furazolidone: A case report and review of the literature.
Contact Dermatitis
; 89(6): 496-500, 2023 Dec.
Article
em En
| MEDLINE
| ID: mdl-37750438
ABSTRACT
BACKGROUND:
Furazolidone is a nitrofuran antimicrobial agent used in the treatment of bacterial and protozoal infections. Hypersensitivity to furazolidone is rarely reported and only eight cases have been documented in English since 1967.OBJECTIVES:
To report a 24-year-old man who developed exanthematous drug eruptions in general and swelling sensation of the hands after first dose of oral administration of medicines for Helicobacter pylori infection 7 h later, who was finally confirmed with delayed-type IV allergic reaction to furazolidone by provocation tests. And to review the existing literature.METHODS:
Thorough clinical examination, prick, intradermal, and patch tests, drug provocation tests were performed in the patient.RESULTS:
Skin tests of all used drugs were negative. Drug provocation tests to furazolidone resulted to be positive.CONCLUSIONS:
Clinicians should be aware that furazolidone may induce delayed-type allergic reactions; diagnostic approaches should be taken to identify the responsible drug when multiple medications were used concurrently.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Helicobacter pylori
/
Infecções por Helicobacter
/
Dermatite Alérgica de Contato
/
Hipersensibilidade a Drogas
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Contact Dermatitis
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
China