Chemotaxis: Dendritic cells as trendsetters of the immune response.

Shergold, Amy L; Devlin, Ryan M; Young, Alex L; Roberts, Ed W

Shergold, Amy L; Devlin, Ryan M; Young, Alex L; Roberts, Ed W.

Afiliação

Shergold AL; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, UK.
Devlin RM; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, UK.
Young AL; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, UK.
Roberts EW; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, UK; School of Cancer Studies, University of Glasgow, Glasgow, UK. Electronic address: ed.roberts@glasgow.ac.uk.

Curr Biol ; 33(18): R957-R959, 2023 09 25.

Article em En | MEDLINE | ID: mdl-37751709

ABSTRACT

ABSTRACT

A new study reports that dendritic cells actively shape the CCL19 chemokine gradient to which they respond and that the chemokine receptor CCR7 both senses CCL19 and mediates its internalisation. Generation of local changes in chemokines allows coordination of movement over longer distances than previous models could explain.

Assuntos

Quimiotaxia; Mecanismos de Defesa; Movimento; Imunidade; Células Dendríticas

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quimiotaxia / Mecanismos de Defesa Idioma: En Revista: Curr Biol Assunto da revista: BIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido

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