Chiisanoside Mediates the Parkin/ZNF746/PGC-1&#945; Axis by Downregulating MiR-181a to Improve Mitochondrial Biogenesis in 6-OHDA-Caused Neurotoxicity Models In Vitro and In Vivo: Suggestions for Prevention of Parkinson's Disease.

Hsu, Yu-Ling; Chen, Hui-Jye; Gao, Jia-Xin; Yang, Ming-Yang; Fu, Ru-Huei

Chiisanoside Mediates the Parkin/ZNF746/PGC-1α Axis by Downregulating MiR-181a to Improve Mitochondrial Biogenesis in 6-OHDA-Caused Neurotoxicity Models In Vitro and In Vivo: Suggestions for Prevention of Parkinson's Disease.

Hsu, Yu-Ling; Chen, Hui-Jye; Gao, Jia-Xin; Yang, Ming-Yang; Fu, Ru-Huei.

Afiliação

Hsu YL; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.
Chen HJ; Department of Laboratory Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan 33305, Taiwan.
Gao JX; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.
Yang MY; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.
Fu RH; Ph.D. Program for Aging, China Medical University, Taichung 40402, Taiwan.

Antioxidants (Basel) ; 12(9)2023 Sep 20.

Article em En | MEDLINE | ID: mdl-37760085

Palavras-chave

6-hydroxydopamine; C. elegans; PGC-1α; Parkinson disease; SH-SY5Y cell; ZNF746; chiisanoside; miR-181a; mitochondrial biogenesis; parkin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Antioxidants (Basel) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Taiwan

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