The repeated administration of rhIL-12 for 14 weeks in rhesus monkeys: A toxicity assessment.

Ding, Huiqin; Qin, Huan; Wang, Jiangang; Dong, Yansheng; Wang, Quanjun; Han, Yantao

Ding, Huiqin; Qin, Huan; Wang, Jiangang; Dong, Yansheng; Wang, Quanjun; Han, Yantao.

Afiliação

Ding H; School of Basic Medical Sciences, Qingdao University, Qingdao, China.
Qin H; Kanglitai Biopharmaceutical (Qingdao) Co., Ltd., Qingdao, China.
Wang J; School of Basic Medical Sciences, Qingdao University, Qingdao, China.
Dong Y; School of Basic Medical Sciences, Qingdao University, Qingdao, China.
Wang Q; Kanglitai Biopharmaceutical (Qingdao) Co., Ltd., Qingdao, China.
Han Y; National Beijing Center for Drug Safety and Research, Beijing Institute of Pharmacology and Toxicology, Beijing, China.

J Appl Toxicol ; 44(2): 301-312, 2024 Feb.

Article em En | MEDLINE | ID: mdl-37770382

Assuntos

Antineoplásicos; Interleucina-12; Animais; Humanos; Macaca mulatta; Proteínas Recombinantes/toxicidade; Interleucina-12/toxicidade; Células Matadoras Naturais

Palavras-chave

IL-12; repeated administration; rhesus monkeys; toxicity; toxicokinetics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-12 / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: J Appl Toxicol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

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