Respiratory Distress Caused by Neoplastic Upper Respiratory Tract Obstructions in 2 Pet Rats (Rattus norvegicus domestica).
Top Companion Anim Med
; 58: 100823, 2024.
Article
em En
| MEDLINE
| ID: mdl-37802245
ABSTRACT
Respiratory disease is one of the primary reasons for pet owners to seek veterinary attention for their rats. While chronic respiratory disease complex is most often responsible for respiratory signs in pet rats and is well characterized, upper respiratory obstructive disease has been rarely reported in the literature. This report describes 2 pet fancy rats (Rattus norvegicus domestica) presenting with a several day history of progressive respiratory signs that were minimally responsive to supportive therapies, including antibiotics, nonsteroidal anti-inflammatories, and fluid and oxygen support. Survey radiographs were performed under sedation in both cases. In the first case, no cause for the clinical signs could be identified, in part due to suboptimal radiographic positioning, although severe aerophagia was noted. In the second case, cervical tracheal luminal narrowing and increased soft tissue opacity along the walls of the trachea were identified. Both rats declined while under sedation, resulting in cardiopulmonary arrest in the first case and humane euthanasia in the second. On necropsy, the first case had a oropharyngeal squamous cell carcinoma originating from the Zymbal's gland, which was obstructing the larynx. The second case had an intra-luminal tracheal mass obstructing the airway. This was mostly likely B-cell lymphoma or a plasma cell tumor, although definitive diagnosis was unable to be obtained. For future such cases empiric management of respiratory disease in rats with antimicrobials, anti-inflammatories, and supportive care is often appropriate based on the high prevalence of infectious agents, however, other noninfectious causes should be considered, such as neoplastic processes leading to upper airway obstructive disease and diagnostic imaging may be indicated.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome do Desconforto Respiratório
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Doenças dos Roedores
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Obstrução das Vias Respiratórias
Tipo de estudo:
Prognostic_studies
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Risk_factors_studies
Limite:
Animals
Idioma:
En
Revista:
Top Companion Anim Med
Assunto da revista:
MEDICINA VETERINARIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos