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Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2, and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand.
Martin, Eleyna M; Clark, Joanne C; Montague, Samantha J; Morán, Luis A; Di, Ying; Bull, Lily J; Whittle, Luke; Raka, Florije; Buka, Richard J; Zafar, Idrees; Kardeby, Caroline; Slater, Alexandre; Watson, Steve P.
Afiliação
  • Martin EM; Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston, Birmingham, UK. Electronic address: e.martin.2@bham.ac.uk.
  • Clark JC; Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston, Birmingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), The Universities of Birmingham and Nottingham, The Midlands, UK.
  • Montague SJ; Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
  • Morán LA; Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
  • Di Y; Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
  • Bull LJ; Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
  • Whittle L; Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
  • Raka F; Institute for Transfusion Medicine-Skopje, Skopje, North Macedonia.
  • Buka RJ; Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
  • Zafar I; Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
  • Kardeby C; Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston, Birmingham, UK; Current address: School of Biosciences, College of Health and Life Sciences, Aston University, Birmingham, UK.
  • Slater A; Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
  • Watson SP; Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston, Birmingham, UK; Centre of Membrane Proteins and Receptors (COMPARE), The Universities of Birmingham and Nottingham, The Midlands, UK. Electronic address: s.p.watson@bham.ac.uk.
J Thromb Haemost ; 22(1): 271-285, 2024 Jan.
Article em En | MEDLINE | ID: mdl-37813196
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Anticorpos de Domínio Único Limite: Animals / Humans Idioma: En Revista: J Thromb Haemost Assunto da revista: HEMATOLOGIA Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Anticorpos de Domínio Único Limite: Animals / Humans Idioma: En Revista: J Thromb Haemost Assunto da revista: HEMATOLOGIA Ano de publicação: 2024 Tipo de documento: Article