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Harnessing the power of synthetic data in healthcare: innovation, application, and privacy.
Giuffrè, Mauro; Shung, Dennis L.
Afiliação
  • Giuffrè M; Department of Medicine (Digestive Diseases), Yale School of Medicine, Yale University, New Haven, CT, USA. mauro.giuffre@yale.edu.
  • Shung DL; Department of Medical, Surgical and Health Science, University of Trieste, Trieste, Italy. mauro.giuffre@yale.edu.
NPJ Digit Med ; 6(1): 186, 2023 Oct 09.
Article em En | MEDLINE | ID: mdl-37813960
Data-driven decision-making in modern healthcare underpins innovation and predictive analytics in public health and clinical research. Synthetic data has shown promise in finance and economics to improve risk assessment, portfolio optimization, and algorithmic trading. However, higher stakes, potential liabilities, and healthcare practitioner distrust make clinical use of synthetic data difficult. This paper explores the potential benefits and limitations of synthetic data in the healthcare analytics context. We begin with real-world healthcare applications of synthetic data that informs government policy, enhance data privacy, and augment datasets for predictive analytics. We then preview future applications of synthetic data in the emergent field of digital twin technology. We explore the issues of data quality and data bias in synthetic data, which can limit applicability across different applications in the clinical context, and privacy concerns stemming from data misuse and risk of re-identification. Finally, we evaluate the role of regulatory agencies in promoting transparency and accountability and propose strategies for risk mitigation such as Differential Privacy (DP) and a dataset chain of custody to maintain data integrity, traceability, and accountability. Synthetic data can improve healthcare, but measures to protect patient well-being and maintain ethical standards are key to promote responsible use.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline / Prognostic_studies / Risk_factors_studies Idioma: En Revista: NPJ Digit Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline / Prognostic_studies / Risk_factors_studies Idioma: En Revista: NPJ Digit Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos