Metabolite profiling and identification of enzymes responsible for the metabolism of hirsutine, a major alkaloid from <i>Uncaria rhynchophylla</i>.

Guo, Yiqing; Lv, Huanhuan; Lv, Jing; Jiang, Zenghong

Metabolite profiling and identification of enzymes responsible for the metabolism of hirsutine, a major alkaloid from Uncaria rhynchophylla.

Guo, Yiqing; Lv, Huanhuan; Lv, Jing; Jiang, Zenghong.

Afiliação

Guo Y; Henan University of Chinese Medicine, Zhengzhou, China.
Lv H; The Third Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, China.
Lv J; People's Hospital of Zhengzhou, Zhengzhou, China.
Jiang Z; School of Medicine, Hefei Technology College, Chaohu City, China.

Xenobiotica ; 53(6-7): 474-483, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37819730

Assuntos

Alcaloides; Antineoplásicos; Uncaria; Humanos; Alcaloides/farmacologia; Sistema Enzimático do Citocromo P-450/metabolismo; Antineoplásicos/metabolismo; Microssomos Hepáticos/metabolismo

Palavras-chave

3-methyleneindolenine; Hirsutine; LC-HRMS; iminoquinone; metabolic pathway

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Uncaria / Alcaloides / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Xenobiotica Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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