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Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections.
Reinke, Patrick Y A; de Souza, Edmarcia Elisa; Günther, Sebastian; Falke, Sven; Lieske, Julia; Ewert, Wiebke; Loboda, Jure; Herrmann, Alexander; Rahmani Mashhour, Aida; Karnicar, Katarina; Usenik, Aleksandra; Lindic, Natasa; Sekirnik, Andreja; Botosso, Viviane Fongaro; Santelli, Gláucia Maria Machado; Kapronezai, Josana; de Araújo, Marcelo Valdemir; Silva-Pereira, Taiana Tainá; Filho, Antônio Francisco de Souza; Tavares, Mariana Silva; Flórez-Álvarez, Lizdany; de Oliveira, Danielle Bruna Leal; Durigon, Edison Luiz; Giaretta, Paula Roberta; Heinemann, Marcos Bryan; Hauser, Maurice; Seychell, Brandon; Böhler, Hendrik; Rut, Wioletta; Drag, Marcin; Beck, Tobias; Cox, Russell; Chapman, Henry N; Betzel, Christian; Brehm, Wolfgang; Hinrichs, Winfried; Ebert, Gregor; Latham, Sharissa L; Guimarães, Ana Marcia de Sá; Turk, Dusan; Wrenger, Carsten; Meents, Alke.
Afiliação
  • Reinke PYA; Center for Free-Electron Laser Science CFEL, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
  • de Souza EE; Department of Parasitology, Institute of Biomedical Sciences at the University of São Paulo, São Paulo, Brazil.
  • Günther S; Center for Free-Electron Laser Science CFEL, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
  • Falke S; Center for Free-Electron Laser Science CFEL, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
  • Lieske J; Center for Free-Electron Laser Science CFEL, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
  • Ewert W; Center for Free-Electron Laser Science CFEL, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
  • Loboda J; Department of Biochemistry and Molecular and Structural Biology, Jozef Stefan Institute, Jamova 39, 1000, Ljubljana, Slovenia.
  • Herrmann A; Jozef Stefan International Postgraduate School, Jamova 39, Ljubljana, Slovenia.
  • Rahmani Mashhour A; Institute of Virology, Helmholtz Munich, Munich, Germany.
  • Karnicar K; Center for Free-Electron Laser Science CFEL, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
  • Usenik A; Department of Biochemistry and Molecular and Structural Biology, Jozef Stefan Institute, Jamova 39, 1000, Ljubljana, Slovenia.
  • Lindic N; Centre of Excellence for Integrated Approaches in Chemistry and Biology of Proteins, Jamova 39, 1000, Ljubljana, Slovenia.
  • Sekirnik A; Department of Biochemistry and Molecular and Structural Biology, Jozef Stefan Institute, Jamova 39, 1000, Ljubljana, Slovenia.
  • Botosso VF; Centre of Excellence for Integrated Approaches in Chemistry and Biology of Proteins, Jamova 39, 1000, Ljubljana, Slovenia.
  • Santelli GMM; Department of Biochemistry and Molecular and Structural Biology, Jozef Stefan Institute, Jamova 39, 1000, Ljubljana, Slovenia.
  • Kapronezai J; Department of Biochemistry and Molecular and Structural Biology, Jozef Stefan Institute, Jamova 39, 1000, Ljubljana, Slovenia.
  • de Araújo MV; Virology Laboratory, Center of Development and Innovation, Butantan Institute, São Paulo, Brazil.
  • Silva-Pereira TT; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Filho AFS; Virology Laboratory, Center of Development and Innovation, Butantan Institute, São Paulo, Brazil.
  • Tavares MS; Virology Laboratory, Center of Development and Innovation, Butantan Institute, São Paulo, Brazil.
  • Flórez-Álvarez L; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • de Oliveira DBL; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Durigon EL; Department of Preventive Veterinary Medicine and Animal Health, College of Veterinary Medicine, University of São Paulo, São Paulo, Brazil.
  • Giaretta PR; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Heinemann MB; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Hauser M; Department of Parasitology, Institute of Biomedical Sciences at the University of São Paulo, São Paulo, Brazil.
  • Seychell B; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Böhler H; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Rut W; Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, 4474 TAMU, School Station, TX, USA.
  • Drag M; Department of Preventive Veterinary Medicine and Animal Health, College of Veterinary Medicine, University of São Paulo, São Paulo, Brazil.
  • Beck T; Institute for Organic Chemistry and BMWZ, Leibniz University of Hannover, Schneiderberg 38, 30167, Hannover, Germany.
  • Cox R; Department of Chemistry, Institute of Physical Chemistry, Universität Hamburg, Grindelallee 117, 20146, Hamburg, Germany.
  • Chapman HN; Department of Chemistry, Institute of Physical Chemistry, Universität Hamburg, Grindelallee 117, 20146, Hamburg, Germany.
  • Betzel C; Department of Chemical Biology and Bioimaging, Faculty of Chemistry, Wroclaw University of Science and Technology, Wybrzeze Wyspianskiego 27, 50-370, Wroclaw, Poland.
  • Brehm W; Department of Chemical Biology and Bioimaging, Faculty of Chemistry, Wroclaw University of Science and Technology, Wybrzeze Wyspianskiego 27, 50-370, Wroclaw, Poland.
  • Hinrichs W; Department of Chemistry, Institute of Physical Chemistry, Universität Hamburg, Grindelallee 117, 20146, Hamburg, Germany.
  • Ebert G; Hamburg Centre for Ultrafast Imaging, Universität Hamburg, Luruper Chaussee 149, 22761, Hamburg, Germany.
  • Latham SL; Institute for Organic Chemistry and BMWZ, Leibniz University of Hannover, Schneiderberg 38, 30167, Hannover, Germany.
  • Guimarães AMS; Center for Free-Electron Laser Science CFEL, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
  • Turk D; Hamburg Centre for Ultrafast Imaging, Universität Hamburg, Luruper Chaussee 149, 22761, Hamburg, Germany.
  • Wrenger C; Department of Physics, Universität Hamburg, Luruper Chaussee 149, 22761, Hamburg, Germany.
  • Meents A; Hamburg Centre for Ultrafast Imaging, Universität Hamburg, Luruper Chaussee 149, 22761, Hamburg, Germany.
Commun Biol ; 6(1): 1058, 2023 10 18.
Article em En | MEDLINE | ID: mdl-37853179
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 Limite: Humans Idioma: En Revista: Commun Biol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 Limite: Humans Idioma: En Revista: Commun Biol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha