Pathophysiologic Insights into the Transition from Asymptomatic Bacteriuria to Urinary Tract Infection.
Curr Urol Rep
; 24(11): 533-540, 2023 Nov.
Article
em En
| MEDLINE
| ID: mdl-37856072
ABSTRACT
PURPOSE OF REVIEW Asymptomatic bacteriuria (ASB) can be found in the general population but it is more common in catheterized patients. Some patients develop urinary tract infections (UTI) and others stay asymptomatic throughout time. The scientific community lacks a pathophysiologic explanation of why asymptomatic bacteriuria stays asymptomatic most of the time, and why and how it sometimes transitions to UTI. In an attempt to bridge this gap in knowledge, a summary of the current literature is conducted on the pathophysiologic differences between ASB and UTI, beyond their clinical differences. RECENT FINDINGS:
ASB and UTI cannot be differentiated just by their phylogroup or number of virulence factors. The difference may be in their metabolism gene expression. The literature lacks a pathophysiological explanation of the transition from ASB to UTI, and recent discoveries suggest that metabolic gene expression may hold the key.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bacteriúria
/
Infecções Urinárias
/
Infecções Relacionadas a Cateter
Limite:
Humans
Idioma:
En
Revista:
Curr Urol Rep
Assunto da revista:
UROLOGIA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Estados Unidos