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A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response.
Subramanian, Advait; Wang, Lan; Moss, Tom; Voorhies, Mark; Sangwan, Smriti; Stevenson, Erica; Pulido, Ernst H; Kwok, Samentha; Chalkley, Robert J; Li, Kathy H; Krogan, Nevan J; Swaney, Danielle L; Burlingame, Alma L; Floor, Stephen N; Sil, Anita; Walter, Peter; Mukherjee, Shaeri.
Afiliação
  • Subramanian A; G.W. Hooper Foundation, University of California at San Francisco, San Francisco, CA, USA.
  • Wang L; Department of Microbiology and Immunology, University of California at San Francisco, San Francisco, CA, USA.
  • Moss T; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, CA, USA.
  • Voorhies M; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, CA, USA.
  • Sangwan S; G.W. Hooper Foundation, University of California at San Francisco, San Francisco, CA, USA.
  • Stevenson E; Department of Microbiology and Immunology, University of California at San Francisco, San Francisco, CA, USA.
  • Pulido EH; Department of Microbiology and Immunology, University of California at San Francisco, San Francisco, CA, USA.
  • Kwok S; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, CA, USA.
  • Chalkley RJ; Gladstone Institute of Data Science and Biotechnology, J. Gladstone Institutes, San Francisco, CA, USA.
  • Li KH; Department of Cellular and Molecular Pharmacology, University of California at San Francisco, San Francisco, CA, USA.
  • Krogan NJ; Quantitative Biosciences Institute, University of California at San Francisco, San Francisco, CA, USA.
  • Swaney DL; Gladstone Institute of Data Science and Biotechnology, J. Gladstone Institutes, San Francisco, CA, USA.
  • Burlingame AL; Department of Cell and Tissue Biology, University of California at San Francisco, San Francisco, CA, USA.
  • Floor SN; Mass Spectrometry Facility, Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA, USA.
  • Sil A; Mass Spectrometry Facility, Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA, USA.
  • Walter P; Gladstone Institute of Data Science and Biotechnology, J. Gladstone Institutes, San Francisco, CA, USA.
  • Mukherjee S; Department of Cellular and Molecular Pharmacology, University of California at San Francisco, San Francisco, CA, USA.
Nat Cell Biol ; 25(11): 1600-1615, 2023 Nov.
Article em En | MEDLINE | ID: mdl-37857833
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Legionella / Doença dos Legionários / Legionella pneumophila Limite: Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Legionella / Doença dos Legionários / Legionella pneumophila Limite: Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos