Loss of fragile WWOX gene leads to senescence escape and genome instability.

Cheng, Hui-Ching; Huang, Po-Hsien; Lai, Feng-Jie; Jan, Ming-Shiou; Chen, Yi-Lin; Chen, Szu-Ying; Chen, Wan-Li; Hsu, Chao-Kai; Huang, Wenya; Hsu, Li-Jin

Cheng, Hui-Ching; Huang, Po-Hsien; Lai, Feng-Jie; Jan, Ming-Shiou; Chen, Yi-Lin; Chen, Szu-Ying; Chen, Wan-Li; Hsu, Chao-Kai; Huang, Wenya; Hsu, Li-Jin.

Afiliação

Cheng HC; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan.
Huang PH; Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan.
Lai FJ; Department of Dermatology, Chi Mei Medical Center, Tainan, 71004, Taiwan. lai.fengjie@gmail.com.
Jan MS; Center for General Education, Southern Taiwan University of Science and Technology, Tainan, 71005, Taiwan. lai.fengjie@gmail.com.
Chen YL; Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University, Taichung, 40201, Taiwan.
Chen SY; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan.
Chen WL; Molecular Diagnosis Laboratory, Department of Pathology, National Cheng Kung University Hospital, Tainan, 704302, Taiwan.
Hsu CK; Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan.
Huang W; Molecular Diagnosis Laboratory, Department of Pathology, National Cheng Kung University Hospital, Tainan, 704302, Taiwan.
Hsu LJ; Department of Dermatology, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan.

Cell Mol Life Sci ; 80(11): 338, 2023 Oct 28.

Article em En | MEDLINE | ID: mdl-37897534

Assuntos

Proteína Supressora de Tumor p53; Raios Ultravioleta; Animais; Humanos; Camundongos; Senescência Celular/genética; DNA/metabolismo; Fibroblastos/metabolismo; Instabilidade Genômica; Células HEK293; Proteína Supressora de Tumor p53/genética; Proteína Supressora de Tumor p53/metabolismo; Proteínas Supressoras de Tumor/genética; Proteínas Supressoras de Tumor/metabolismo; Oxidorredutase com Domínios WW/genética; Oxidorredutase com Domínios WW/metabolismo

Palavras-chave

CDK inhibitors; Mononucleotide repeat markers; Promoter hypermethylation; Redox homeostasis; Replicative arrest; Tumor suppressor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Raios Ultravioleta / Proteína Supressora de Tumor p53 Limite: Animals / Humans Idioma: En Revista: Cell Mol Life Sci Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Taiwan

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