Design of experiment (DoE) as a quality by design (QbD) tool to optimise formulations of lipid nanoparticles for nose-to-brain drug delivery.

Correia, A C; Moreira, J N; Sousa Lobo, J M; Silva, A C

Correia, A C; Moreira, J N; Sousa Lobo, J M; Silva, A C.

Afiliação

Correia AC; Faculty of Pharmacy, University of Porto, UCIBIO, REQUIMTE, Porto, Portugal.
Moreira JN; Associate Laboratory i4HB Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, Porto, Portugal.
Sousa Lobo JM; CNC - Center for Neuroscience and Cell Biology, Center for Innovative Biomedicine and Biotechnology (CIBB), Faculty of Medicine (Pólo I), University of Coimbra, Coimbra, Portugal.
Silva AC; Faculty of Pharmacy, Univ Coimbra - University of Coimbra, CIBB, Pólo das Ciências da Saúde, Azinhaga de, Santa Comba, Coimbra, Portugal.

Expert Opin Drug Deliv ; 20(12): 1731-1748, 2023.

Article em En | MEDLINE | ID: mdl-37905547

Assuntos

Portadores de Fármacos; Nanopartículas; Lipídeos; Sistemas de Liberação de Medicamentos; Encéfalo; Tamanho da Partícula

Palavras-chave

Design of experiment; lipid nanoparticles; nanostructured lipid carriers; nose-to-brain; quality-by-design; solid lipid nanoparticles

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Portadores de Fármacos / Nanopartículas Idioma: En Revista: Expert Opin Drug Deliv Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Portugal

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