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iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer.
Park, Dong Shin; Kozaki, Tatsuya; Tiwari, Satish Kumar; Moreira, Marco; Khalilnezhad, Ahad; Torta, Federico; Olivié, Nicolas; Thiam, Chung Hwee; Liani, Oniko; Silvin, Aymeric; Phoo, Wint Wint; Gao, Liang; Triebl, Alexander; Tham, Wai Kin; Gonçalves, Leticia; Kong, Wan Ting; Raman, Sethi; Zhang, Xiao Meng; Dunsmore, Garett; Dutertre, Charles Antoine; Lee, Salanne; Ong, Jia Min; Balachander, Akhila; Khalilnezhad, Shabnam; Lum, Josephine; Duan, Kaibo; Lim, Ze Ming; Tan, Leonard; Low, Ivy; Utami, Kagistia Hana; Yeo, Xin Yi; Di Tommaso, Sylvaine; Dupuy, Jean-William; Varga, Balazs; Karadottir, Ragnhildur Thora; Madathummal, Mufeeda Changaramvally; Bonne, Isabelle; Malleret, Benoit; Binte, Zainab Yasin; Wei Da, Ngan; Tan, Yingrou; Wong, Wei Jie; Zhang, Jinqiu; Chen, Jinmiao; Sobota, Radoslaw M; Howland, Shanshan W; Ng, Lai Guan; Saltel, Frédéric; Castel, David; Grill, Jacques.
Afiliação
  • Park DS; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Kozaki T; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Tiwari SK; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Moreira M; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Khalilnezhad A; INSERM U1015, Gustave Roussy Cancer Campus, Villejuif, France.
  • Torta F; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Olivié N; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Thiam CH; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Liani O; Singapore Lipidomics Incubator (SLING), Life Sciences Institute, National University of Singapore, Singapore, Singapore.
  • Silvin A; Institut de Biologie de l'Ecole Normale Supérieure (IBENS), Ecole Normale Supérieure, CNRS, INSERM, PSL Research University, Paris, France.
  • Phoo WW; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Gao L; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Triebl A; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Tham WK; INSERM U1015, Gustave Roussy Cancer Campus, Villejuif, France.
  • Gonçalves L; Functional Proteomics Laboratory, SingMass National Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore.
  • Kong WT; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Raman S; Singapore Lipidomics Incubator (SLING), Life Sciences Institute, National University of Singapore, Singapore, Singapore.
  • Zhang XM; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Dunsmore G; Singapore Lipidomics Incubator (SLING), Life Sciences Institute, National University of Singapore, Singapore, Singapore.
  • Dutertre CA; Singapore Lipidomics Incubator (SLING), Life Sciences Institute, National University of Singapore, Singapore, Singapore.
  • Lee S; INSERM U1015, Gustave Roussy Cancer Campus, Villejuif, France.
  • Ong JM; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Balachander A; INSERM U1015, Gustave Roussy Cancer Campus, Villejuif, France.
  • Khalilnezhad S; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Lum J; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Duan K; INSERM U1015, Gustave Roussy Cancer Campus, Villejuif, France.
  • Lim ZM; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Tan L; INSERM U1015, Gustave Roussy Cancer Campus, Villejuif, France.
  • Low I; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Utami KH; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Yeo XY; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Di Tommaso S; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Dupuy JW; Translational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore.
  • Varga B; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Karadottir RT; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Madathummal MC; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Bonne I; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Malleret B; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Binte ZY; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research, Singapore, Singapore.
  • Wei Da N; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research, Singapore, Singapore.
  • Tan Y; Oncoprot Platform, TBM-Core US 005, Bordeaux, France.
  • Wong WJ; Bordeaux Protéome, University of Bordeaux, Bordeaux, France.
  • Zhang J; Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute and Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
  • Chen J; Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute and Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
  • Sobota RM; A*STAR Microscopy Platform Electron Microscopy, Research Support Centre, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Howland SW; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Ng LG; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
  • Saltel F; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Castel D; A*STAR Microscopy Platform Electron Microscopy, Research Support Centre, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  • Grill J; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore, Singapore.
Nature ; 623(7986): 397-405, 2023 Nov.
Article em En | MEDLINE | ID: mdl-37914940
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Organoides / Colesterol / Microglia / Neurogênese / Células-Tronco Pluripotentes Induzidas / Células-Tronco Neurais Limite: Animals / Humans Idioma: En Revista: Nature Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Singapura
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Organoides / Colesterol / Microglia / Neurogênese / Células-Tronco Pluripotentes Induzidas / Células-Tronco Neurais Limite: Animals / Humans Idioma: En Revista: Nature Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Singapura