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RNA base editing therapy cures hearing loss induced by OTOF gene mutation.
Xue, Yuanyuan; Tao, Yong; Wang, Xing; Wang, Xueling; Shu, Yilai; Liu, Yuanhua; Kang, Wen; Chen, Sifan; Cheng, Zhenzhe; Yan, Boou; Xie, Yanwei; Bi, Lanting; Jia, Haitao; Li, Jinhui; Xiao, Qingquan; Chen, Liying; Yao, Xuan; Shi, Linyu; Yang, Hui; Wu, Hao.
Afiliação
  • Xue Y; Department of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China; HuidaGene Therapeutics Co., Ltd., Shanghai 200131, China.
  • Tao Y; Department of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China; Ear Institute, Shanghai Jiaotong University School of Medicine, Shanghai 200125, China; Shanghai Key Laboratory of Translational Medicine on
  • Wang X; HuidaGene Therapeutics Co., Ltd., Shanghai 200131, China.
  • Wang X; Department of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China; Ear Institute, Shanghai Jiaotong University School of Medicine, Shanghai 200125, China; Shanghai Key Laboratory of Translational Medicine on
  • Shu Y; ENT Institute and Department of Otorhinolaryngology, Eye and ENT Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200031, China; Institute of Biomedical Science, Fudan University, Shanghai 200032, China; NHC Key Laboratory
  • Liu Y; Institute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
  • Kang W; Department of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China; Ear Institute, Shanghai Jiaotong University School of Medicine, Shanghai 200125, China; Shanghai Key Laboratory of Translational Medicine on
  • Chen S; HuidaGene Therapeutics Co., Ltd., Shanghai 200131, China.
  • Cheng Z; Department of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China; Ear Institute, Shanghai Jiaotong University School of Medicine, Shanghai 200125, China; Shanghai Key Laboratory of Translational Medicine on
  • Yan B; HuidaGene Therapeutics Co., Ltd., Shanghai 200131, China.
  • Xie Y; HuidaGene Therapeutics Co., Ltd., Shanghai 200131, China.
  • Bi L; HuidaGene Therapeutics Co., Ltd., Shanghai 200131, China.
  • Jia H; HuidaGene Therapeutics Co., Ltd., Shanghai 200131, China.
  • Li J; HuidaGene Therapeutics Co., Ltd., Shanghai 200131, China.
  • Xiao Q; HuidaGene Therapeutics Co., Ltd., Shanghai 200131, China.
  • Chen L; HuidaGene Therapeutics Co., Ltd., Shanghai 200131, China.
  • Yao X; HuidaGene Therapeutics Co., Ltd., Shanghai 200131, China.
  • Shi L; HuidaGene Therapeutics Co., Ltd., Shanghai 200131, China.
  • Yang H; HuidaGene Therapeutics Co., Ltd., Shanghai 200131, China; Institute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China. Electronic address: huiyang@huidagene.com.
  • Wu H; Department of Otolaryngology-Head and Neck Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China; Ear Institute, Shanghai Jiaotong University School of Medicine, Shanghai 200125, China; Shanghai Key Laboratory of Translational Medicine on
Mol Ther ; 31(12): 3520-3530, 2023 Dec 06.
Article em En | MEDLINE | ID: mdl-37915172
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Surdez / Perda Auditiva Central / Perda Auditiva Limite: Animals Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Surdez / Perda Auditiva Central / Perda Auditiva Limite: Animals Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China