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Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions.
Zhao, Yu; Coelho, Camila; Hughes, Amanda L; Lazar-Stefanita, Luciana; Yang, Sandy; Brooks, Aaron N; Walker, Roy S K; Zhang, Weimin; Lauer, Stephanie; Hernandez, Cindy; Cai, Jitong; Mitchell, Leslie A; Agmon, Neta; Shen, Yue; Sall, Joseph; Fanfani, Viola; Jalan, Anavi; Rivera, Jordan; Liang, Feng-Xia; Bader, Joel S; Stracquadanio, Giovanni; Steinmetz, Lars M; Cai, Yizhi; Boeke, Jef D.
Afiliação
  • Zhao Y; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY 10016, USA.
  • Coelho C; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY 10016, USA.
  • Hughes AL; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69117 Heidelberg, Germany.
  • Lazar-Stefanita L; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY 10016, USA.
  • Yang S; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY 10016, USA.
  • Brooks AN; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69117 Heidelberg, Germany.
  • Walker RSK; School of Engineering, Institute for Bioengineering, the University of Edinburgh, Edinburgh EH9 3BF.
  • Zhang W; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY 10016, USA.
  • Lauer S; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY 10016, USA.
  • Hernandez C; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY 10016, USA.
  • Cai J; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Mitchell LA; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY 10016, USA.
  • Agmon N; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY 10016, USA.
  • Shen Y; BGI, Shenzhen, Beishan, Industrial Zone, Shenzhen 518083, China; Guangdong Provincial Key Laboratory of Genome Read and Write, BGI, Shenzhen, Shenzhen 518120, China.
  • Sall J; Microscopy Laboratory, NYU Langone Health, New York, NY 10016, USA.
  • Fanfani V; School of Biological Sciences, the University of Edinburgh, Edinburgh EH9 3BF.
  • Jalan A; Department of Biology, New York University, New York, NY, USA.
  • Rivera J; Department of Biology, New York University, New York, NY, USA.
  • Liang FX; Microscopy Laboratory, NYU Langone Health, New York, NY 10016, USA.
  • Bader JS; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Stracquadanio G; School of Biological Sciences, the University of Edinburgh, Edinburgh EH9 3BF.
  • Steinmetz LM; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69117 Heidelberg, Germany; Department of Genetics and Stanford Genome Technology Center, Stanford University, Palo Alto, CA 94304, USA.
  • Cai Y; Manchester Institute of Biotechnology, the University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.
  • Boeke JD; Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY 10016, USA; Department of Biomedical Engineering, NYU Tandon School of Engineering, Brooklyn, New York, NY 11201, USA. Electronic address: jef.boeke@nyulangone.org.
Cell ; 186(24): 5220-5236.e16, 2023 11 22.
Article em En | MEDLINE | ID: mdl-37944511
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Genoma Fúngico / Cromossomos Artificiais de Levedura Idioma: En Revista: Cell Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Genoma Fúngico / Cromossomos Artificiais de Levedura Idioma: En Revista: Cell Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos