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Neuron-specific gene NSG1 binds to and positively regulates sortilin ectodomain shedding via a metalloproteinase-dependent mechanism.
Overby, Malene; Serrano-Rodriguez, Antonio; Dadras, Somayeh; Christiansen, Ann Kathrine; Ozcelik, Gözde; Lichtenthaler, Stefan F; Weick, Jason Porter; Müller, Heidi Kaastrup.
Afiliação
  • Overby M; Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Serrano-Rodriguez A; Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
  • Dadras S; Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
  • Christiansen AK; Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Ozcelik G; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany; Neuroproteomics, School of Medicine, Klinikum Rechts der lsar, Technical University of Munich, Munich, Germany.
  • Lichtenthaler SF; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany; Neuroproteomics, School of Medicine, Klinikum Rechts der lsar, Technical University of Munich, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
  • Weick JP; Department of Neurosciences, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA.
  • Müller HK; Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark. Electronic address: heidi.muller@clin.au.dk.
J Biol Chem ; 299(12): 105446, 2023 Dec.
Article em En | MEDLINE | ID: mdl-37949230
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Proteínas Adaptadoras de Transporte Vesicular / Metaloproteases / Proteínas do Tecido Nervoso / Neurônios Idioma: En Revista: J Biol Chem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Proteínas Adaptadoras de Transporte Vesicular / Metaloproteases / Proteínas do Tecido Nervoso / Neurônios Idioma: En Revista: J Biol Chem Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca