Determination of seroprevalence and kinetics of humoral response using mpox virus A29 protein.

Cai, Jian-Piao; Chu, Wing-Ming; Tam, Anthony Raymond; Wang, Kun; Han, Yuting; Chen, Lin-Lei; Zhang, Xiaojuan; Choi, Charlotte Yee-Ki; Cheng, Vincent Chi-Chung; Chan, Kwok-Hung; Chen, Zhiwei; Hung, Ivan Fan-Ngai; Fong, Carol Ho-Yan; To, Kelvin Kai-Wang

Cai, Jian-Piao; Chu, Wing-Ming; Tam, Anthony Raymond; Wang, Kun; Han, Yuting; Chen, Lin-Lei; Zhang, Xiaojuan; Choi, Charlotte Yee-Ki; Cheng, Vincent Chi-Chung; Chan, Kwok-Hung; Chen, Zhiwei; Hung, Ivan Fan-Ngai; Fong, Carol Ho-Yan; To, Kelvin Kai-Wang.

Afiliação

Cai JP; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
Chu WM; Infectious Diseases Division, Department of Medicine, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region, China.
Tam AR; Infectious Diseases Division, Department of Medicine, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region, China.
Wang K; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
Han Y; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
Chen LL; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
Zhang X; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
Choi CY; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
Cheng VC; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
Chan KH; Department of Microbiology, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region, China.
Chen Z; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
Hung IF; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong Special Administrative Region, China.
Fong CH; State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
To KK; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong Special Administrative Region, China.

Commun Med (Lond) ; 3(1): 168, 2023 Nov 22.

Article em En | MEDLINE | ID: mdl-37993690

Since early 2022, mpox (monkeypox) has been reported in many countries where the disease is not regularly found to occur. The aim of the study was to develop and evaluate the performance of laboratory assays based on the mpox virus surface protein, named A29. We found our assays could accurately distinguish naturally infected cases from smallpox vaccine recipients as well as those who were neither infected nor vaccinated. Our assays provide a useful tool for studying the host immune response to mpox virus.

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Commun Med (Lond) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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