Novel Covalent Modifier-Induced Local Conformational Changes within the Intrinsically Disordered Region of the Androgen Receptor.

Harnish, Michael T; Lopez, Daniel; Morrison, Corbin T; Narayanan, Ramesh; Fernandez, Elias J; Shen, Tongye

Harnish, Michael T; Lopez, Daniel; Morrison, Corbin T; Narayanan, Ramesh; Fernandez, Elias J; Shen, Tongye.

Afiliação

Harnish MT; Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996, USA.
Lopez D; Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996, USA.
Morrison CT; Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996, USA.
Narayanan R; Department of Medicine, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Fernandez EJ; Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996, USA.
Shen T; Department of Biochemistry & Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996, USA.

Biology (Basel) ; 12(11)2023 Nov 17.

Article em En | MEDLINE | ID: mdl-37998041

Palavras-chave

androgen receptor; covalent drug; intrinsically disordered protein; molecular dynamics simulation; protein conformation

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Biology (Basel) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google