Effects of intracordal trafermin injection on mutational voice disorder.
Am J Otolaryngol
; 45(2): 104139, 2024.
Article
em En
| MEDLINE
| ID: mdl-38101138
ABSTRACT
INTRODUCTION:
Mutational voice disorder is the inability of the voice to adjust to the changes in the larynx during puberty, resulting in the speaking fundamental frequency failing to decrease. Standard treatments for mutational voice disorder are voice therapy and thyroplasty. However, voice therapy takes time to show its effects, and thyroplasty is highly invasive. Herein, we present a case of mutational voice disorder successfully treated with intracordal trafermin injection. CASESUMMARY:
A 31-year-old male patient was diagnosed with mutational voice disorder and offered standard treatment, but he requested a less invasive treatment with early effects. We performed intracordal trafermin injection with his consent. Two months after the procedure, the speaking fundamental frequency decreased from 155.5 Hz to 93.0 Hz, and the voice handicap index decreased from 14 to 2.DISCUSSION:
This case suggests that intracordal trafermin injection is an effective treatment option for mutational voice disorder. Furthermore, compared with the standard treatment methods, it is less invasive and provides effects shortly with only one injection.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fragmentos de Peptídeos
/
Voz
/
Distúrbios da Voz
/
Fatores de Crescimento de Fibroblastos
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Am J Otolaryngol
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Japão