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Azide-free cyclization reaction access to 4-aryl-NH-1,2,3-triazoles: P-toluenesulfonyl hydrazide and sulfamic acid as nitrogen sources.
Li, Min; Wan, Qing-Yu; Lin, Ri-Lan; Peng, Yan-Qing; Shu, Wen-Ming; Yu, Wei-Chu; Wu, An-Xin.
Afiliação
  • Li M; Hubei Engineering Research Centers for Clean Production and Pollution Control of Oil and Gas Fields, College of Chemistry and Environmental Engineering, Yangtze University, Jingzhou 434023, P. R. China. shuwm@yangtzeu.edu.cn.
  • Wan QY; Hubei Engineering Research Centers for Clean Production and Pollution Control of Oil and Gas Fields, College of Chemistry and Environmental Engineering, Yangtze University, Jingzhou 434023, P. R. China. shuwm@yangtzeu.edu.cn.
  • Lin RL; Hubei Engineering Research Centers for Clean Production and Pollution Control of Oil and Gas Fields, College of Chemistry and Environmental Engineering, Yangtze University, Jingzhou 434023, P. R. China. shuwm@yangtzeu.edu.cn.
  • Peng YQ; Hubei Engineering Research Centers for Clean Production and Pollution Control of Oil and Gas Fields, College of Chemistry and Environmental Engineering, Yangtze University, Jingzhou 434023, P. R. China. shuwm@yangtzeu.edu.cn.
  • Shu WM; Hubei Engineering Research Centers for Clean Production and Pollution Control of Oil and Gas Fields, College of Chemistry and Environmental Engineering, Yangtze University, Jingzhou 434023, P. R. China. shuwm@yangtzeu.edu.cn.
  • Yu WC; Hubei Engineering Research Centers for Clean Production and Pollution Control of Oil and Gas Fields, College of Chemistry and Environmental Engineering, Yangtze University, Jingzhou 434023, P. R. China. shuwm@yangtzeu.edu.cn.
  • Wu AX; National Key Laboratory of Green Pesticide, International Joint Research Center for Intelligent Biosensor Technology and Health, Central China Normal University, Wuhan 430079, P.R. China.
Org Biomol Chem ; 22(3): 482-485, 2024 Jan 17.
Article em En | MEDLINE | ID: mdl-38108209
ABSTRACT
An iodine-mediated cyclization has been developed to 4-aryl-NH-1,2,3-triazoles, with p-toluenesulfonyl hydrazide and sulfamic acid used as nitrogen sources. Sulfamic acid plays a crucial role in this reaction by both acting as a substrate and providing an acidic environment. This reaction offers a metal- and azide-free strategy to access NH-1,2,3-triazoles.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Org Biomol Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Org Biomol Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2024 Tipo de documento: Article