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Refractory Cytomegalovirus Colitis Followed by De Novo Inflammatory Bowel Disease Post-Orthotopic Liver Transplantation.
Selvan, Bharathi; Pendse, Avani A; Zhang, Cecelia; Cauthen, Jeffriann; Kappus, Matthew R; Messina, Julia A.
Afiliação
  • Selvan B; Duke University School of Medicine, Durham, NC.
  • Pendse AA; Department of Pathology, Duke University School of Medicine, Durham, NC.
  • Zhang C; Division of Gastroenterology, Department of Medicine, Duke University School of Medicine, Durham, NC.
  • Cauthen J; Division of Gastroenterology, Department of Medicine, Duke University School of Medicine, Durham, NC.
  • Kappus MR; Division of Gastroenterology, Department of Medicine, Duke University School of Medicine, Durham, NC.
  • Messina JA; Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC.
ACG Case Rep J ; 10(12): e01232, 2023 Dec.
Article em En | MEDLINE | ID: mdl-38111784
ABSTRACT
Cytomegalovirus (CMV) and inflammatory bowel disease (IBD) are both immune-mediated complications that affect orthotopic liver transplantation patients. In this report, we present a 60-year-old man who underwent orthotopic liver transplantation for cryptogenic cirrhosis with serologies notable for CMV-seropositive donor and seronegative recipient. His post-transplant course was initially complicated by probable refractory CMV colitis. However, his gastrointestinal symptoms persisted, eventually leading to a diagnosis of post-transplant de novo IBD. The discussion highlights theories regarding the association between CMV and IBD, a topic that has been widely debated for decades.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACG Case Rep J Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACG Case Rep J Ano de publicação: 2023 Tipo de documento: Article