Improved test-retest reliability of R 2 * $$ {\mathrm{R}}_2
Magn Reson Med
; 91(6): 2310-2319, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38156825
ABSTRACT
PURPOSE:
This study aimed to evaluate the potential of 3D EPI for improving the reliability of T 2 * $$ {\mathrm{T}}_2^{\ast } $$ -weighted data and quantification of R 2 * $$ {\mathrm{R}}_2^{\ast } $$ decay rate and susceptibility (χ) compared with conventional gradient-echo (GRE)-based acquisition.METHODS:
Eight healthy subjects in a wide age range were recruited. Each subject received repeated scans for both GRE and EPI acquisitions with an isotropic 1 mm resolution at 3 T. Maps of R 2 * $$ {\mathrm{R}}_2^{\ast } $$ and χ were quantified, and their interscan differences were used to evaluate the test-retest reliability. Interprotocol differences of R 2 * $$ {\mathrm{R}}_2^{\ast } $$ and χ between GRE and EPI were also measured voxel by voxel and in selected regions of interest to test the consistency between the two acquisition methods.RESULTS:
The quantifications of R 2 * $$ {\mathrm{R}}_2^{\ast } $$ and χ using EPI protocols showed increased test-retest reliability with higher EPI factors up to 5 as performed in the experiment and were consistent with those based on GRE.CONCLUSION:
The result suggests that multishot multi-echo 3D EPI can be a useful alternative acquisition method for T 2 * $$ {\mathrm{T}}_2^{\ast } $$ -weighted MRI and quantification of R 2 * $$ {\mathrm{R}}_2^{\ast } $$ and χ with reduced scan time, improved test-retest reliability, and similar accuracy compared with commonly used 3D GRE.Palavras-chave
<ns0:math> <semantics> <mrow> <msubsup> <mi>R</mi> <mn>2</mn> <mo>*</mo> </msubsup> </mrow> <annotation>$$ {\mathrm{R}}_2^{\ast } $$</annotation> </semantics> </math>; <ns0:math> <semantics> <mrow> <msubsup> <mi>T</mi> <mn>2</mn> <mo>*</mo> </msubsup> </mrow> <annotation>$$ {\mathrm{T}}_2^{\ast } $$</annotation> </semantics> </math>weighted MRI; 3D EPI; 3D GRE; QSM; testretest reliability
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imageamento por Ressonância Magnética
/
Imagem Ecoplanar
Limite:
Humans
Idioma:
En
Revista:
Magn Reson Med
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos