Ultrasound-dependent kinetics of bone mineralization.

ABSTRACT

Bone Mineral Density (BMD) is an important parameter in the development of orthopedic fracture-healing methods. A recent article (Inoue, S., et al. Bone. 2023, 177, 116916) investigated the use of higher intensity ultrasound to promote murine bone formation by measuring BMD levels. In this work, we present the numerical values of BMD, which show sigmoid kinetics and hyperbolic asymptotic increase with the application of higher intensity ultrasound. Our analysis may provide a foundation for the understanding and application of ultrasound to the human body.