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Liver transplantation meets gastrointestinal cancer.
Loosen, Sven H; Leyh, Catherine; Neumann, Ulf Peter; Bock, Hans; Weigel, Christian; Luedde, Tom; Roderburg, Christoph.
Afiliação
  • Loosen SH; Department of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Leyh C; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Düsseldorf, Germany.
  • Neumann UP; Department of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Bock H; Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Düsseldorf, Germany.
  • Weigel C; Department of General, Visceral and Transplantation Surgery, University Hospital RWTH Aachen, Aachen, Germany.
  • Luedde T; Department of Surgery and Transplantation, University Hospital Essen, Essen, Germany.
  • Roderburg C; Department of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Z Gastroenterol ; 62(1): 62-72, 2024 Jan.
Article em En | MEDLINE | ID: mdl-38195110
ABSTRACT
Liver transplantation (LT) has emerged as a standard of care for patients with end-stage liver disease, providing a life-saving intervention for patients with severely compromised liver function in both the acute and chronic setting. While LT has also become a routine procedure for early-stage hepatocellular carcinoma (HCC), offering a potential cure by treating both the tumor and the underlying liver disease, its relevance in the context of other malignancies such as cholangiocellular carcinoma (CCA), combined hepatocellular-cholangiocarcinoma (cHCC-CCA) or liver metastases is still the subject of intense debate and no definite recommendations have yet been established. This review summarizes the current therapeutic standards in the context of LT for gastrointestinal malignancies and provides a reflection and outlook on current scientific and clinical developments.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias dos Ductos Biliares / Transplante de Fígado / Colangiocarcinoma / Carcinoma Hepatocelular / Neoplasias Gastrointestinais / Neoplasias Hepáticas Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Z Gastroenterol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias dos Ductos Biliares / Transplante de Fígado / Colangiocarcinoma / Carcinoma Hepatocelular / Neoplasias Gastrointestinais / Neoplasias Hepáticas Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Z Gastroenterol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Alemanha