Treating the Neurologic Manifestations of Wilson's Disease With Liver Transplantation.
Neurohospitalist
; 14(1): 99-103, 2024 Jan.
Article
em En
| MEDLINE
| ID: mdl-38235030
ABSTRACT
Wilson's Disease (WD) manifests with systemic and neuropsychiatric symptoms, caused by an ATP7B genetic mutation, leading to an accumulation of copper. Presentations are diverse and the diagnosis should be considered in anyone under 50 with a new onset movement disorder. Early recognition and treatment can limit morbidity. While liver transplantation (LT) is recommended in WD patients with hepatic failure, its use for pure neurologic indication remains controversial. We present a patient who failed medical management and underwent LT for pure neurologic indications. Subsequent neurologic symptom improvement supports the use of LT for patients with pure neurologic manifestations of WD.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Neurohospitalist
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos