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Documentation of the Patient Characteristics Morbid Obesity and Bariatric Surgery in the Hospital Information System and the Influence on the Number of Medication-Related Problems.
Kingma, Jurjen S; Brenkman, Iris A M; van den Broek, Marcel P H; van den Bemt, Patricia M L A; Janssen, Karin; Knibbe, Catherijne A J; Burgers, Desirée M T.
Afiliação
  • Kingma JS; Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands.
  • Brenkman IAM; Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands.
  • van den Broek MPH; Department of Pharmaceutics, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
  • van den Bemt PMLA; Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands.
  • Janssen K; Department of Pharmaceutics, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
  • Knibbe CAJ; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, Groningen, The Netherlands.
  • Burgers DMT; Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands.
Ann Pharmacother ; : 10600280231226243, 2024 Jan 24.
Article em En | MEDLINE | ID: mdl-38268179
ABSTRACT

BACKGROUND:

As a result of pharmacokinetic changes, individuals with morbid obesity and/or with bariatric surgery may require dose adjustments, additional monitoring or medication should be avoided. Clinical decision support (CDS) may provide automated alerts enabling correct prescribing but requires documentation of these patient characteristics in the Hospital Information System (HIS) to prevent medication-related problems (MRPs).

OBJECTIVE:

The primary objective is to determine the proportion of patients with documentation of the patient characteristics morbid obesity and bariatric surgery in the HIS. The secondary objective is to compare the proportion of patients with an MRP in the group with versus without documentation. Also, the type and severity of MRPs and the medication involved are determined.

METHODS:

A prospective cohort study was performed. Patients admitted to the hospital were identified as morbidly obese and/or with bariatric surgery. In the identified patients, the proportion of patients with documentation of the patient characteristics in the HIS was evaluated as primary outcome. Subsequently, patient records were reviewed for MRPs, which were categorized and associated medication was registered. For the primary objective, descriptive statistics was used. For the secondary outcome, the Fisher's exact test was used.

RESULTS:

In 43 (21.4%, 95% confidence interval [CI] 15.7%-27.1%) of 201 included patient (113 morbid obesity, 70 bariatric surgery and 18 both), the patient characteristics were documented. An MRP occurred in 2.3% versus 13.9% (P = 0.032) of patients with and without documentation, respectively. The most common MRP was underdosing in morbid obesity, while in patients with bariatric surgery it was prescription of contra-indicated medication. CONCLUSION AND RELEVANCE The proportion of patients with documentation of the patient characteristics bariatric surgery and/or morbid obesity in the HIS is low, which appears to be associated with more MRPs. To improve medication safety, it is important to document these patient characteristics.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Ann Pharmacother Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Ann Pharmacother Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Holanda