Your browser doesn't support javascript.
loading
Sex-Related Outcomes of Transcatheter Aortic Valve Implantation With Self-Expanding or Balloon-Expandable Valves: Insights from the OPERA-TAVI Registry.
Adamo, Marianna; Branca, Luca; Pezzola, Elisa; Saia, Francesco; Pilgrim, Thomas; Abdel-Wahab, Mohamed; Garot, Philippe; Gandolfo, Caterina; Fiorina, Claudia; Sammartino, Sofia; Latib, Azeem; Santos, Ignacio Amat; Mylotte, Darren; De Marco, Federico; De Backer, Ole; Franco, Luis Nombela; Akodad, Mariama; Ribichini, Flavio Luciano; Bedogni, Francesco; Laterra, Giulia; Mazzapicchi, Alessandro; Tomii, Daijiro; Laforgia, Pietro; Cannata, Stefano; Scotti, Andrea; Fezzi, Simone; Criscione, Enrico; Poletti, Enrico; Mazzucca, Mattia; Valvo, Roberto; Lunardi, Mattia; Mainardi, Andrea; Andreaggi, Stefano; Quagliana, Angelo; Montarello, Nicholas; Hennessey, Breda; Mon-Noboa, Matias; Meier, David; Sgroi, Carmelo; Reddavid, Claudia Maria; Strazzieri, Orazio; Motta, Silvia Crescenzia; Frittitta, Valentina; Dipietro, Elena; Comis, Alessandro; Melfa, Chiara; Cal, Mariachiara; Thiele, Holger; Webb, John G; Søndergaard, Lars.
Afiliação
  • Adamo M; Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialities, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy. Electronic address: mariannaadamo@hotmail.com.
  • Branca L; Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialities, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
  • Pezzola E; Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialities, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
  • Saia F; Cardiovascular Department, Policlinico S. Orsola, University of Bologna, Bologna, Italy.
  • Pilgrim T; Bern University Hospital, Inselspital, Bern, Switzerland.
  • Abdel-Wahab M; Heart Center Leipzig at University of Leipzig and Leipzig Heart Science, Leipzig, Germany.
  • Garot P; Institut Cardiovasculaire Paris Sud (ICPS), Hôpital Jacques Cartier, Ramsay-Santé, Massy, France.
  • Gandolfo C; Istituto Mediterraneo per i Trapianti e Terapie ad Alta specializzazione (ISMETT), Palermo, Italy.
  • Fiorina C; Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialities, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
  • Sammartino S; Division of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco," Catania, Italy.
  • Latib A; Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.
  • Santos IA; Division of Cardiology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
  • Mylotte D; Department of Cardiology, University Hospital, University of Galway, Ireland.
  • De Marco F; Interventional Cardiology Department, IRCSS Centro Cardiologico Monzino, Milan, Italy.
  • De Backer O; The Heart Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
  • Franco LN; Hospital Clinico San Carlo, Madrid, Spain.
  • Akodad M; Institut Cardiovasculaire Paris Sud (ICPS), Hôpital Jacques Cartier, Ramsay-Santé, Massy, France; Centre for Heart Valve Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
  • Ribichini FL; Division of Cardiology, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.
  • Bedogni F; Division of Cardiology, IRCSS Policlinico San Donato, San Donato Milanese (MI), Italy.
  • Laterra G; Università degli Studi di Enna "Kore," Enna, Italy.
  • Mazzapicchi A; Cardiovascular Department, Policlinico S. Orsola, University of Bologna, Bologna, Italy.
  • Tomii D; Bern University Hospital, Inselspital, Bern, Switzerland.
  • Laforgia P; Institut Cardiovasculaire Paris Sud (ICPS), Hôpital Jacques Cartier, Ramsay-Santé, Massy, France.
  • Cannata S; Istituto Mediterraneo per i Trapianti e Terapie ad Alta specializzazione (ISMETT), Palermo, Italy.
  • Scotti A; Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.
  • Fezzi S; Department of Cardiology, University Hospital, University of Galway, Ireland.
  • Criscione E; Division of Cardiology, IRCSS Policlinico San Donato, San Donato Milanese (MI), Italy.
  • Poletti E; Division of Cardiology, IRCSS Policlinico San Donato, San Donato Milanese (MI), Italy.
  • Mazzucca M; Division of Cardiology, IRCSS Policlinico San Donato, San Donato Milanese (MI), Italy.
  • Valvo R; Division of Cardiology, IRCSS Policlinico San Donato, San Donato Milanese (MI), Italy.
  • Lunardi M; Division of Cardiology, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.
  • Mainardi A; Division of Cardiology, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.
  • Andreaggi S; Division of Cardiology, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.
  • Quagliana A; The Heart Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
  • Montarello N; The Heart Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
  • Hennessey B; Hospital Clinico San Carlo, Madrid, Spain.
  • Mon-Noboa M; Hospital Clinico San Carlo, Madrid, Spain.
  • Meier D; Centre for Heart Valve Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
  • Sgroi C; Division of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco," Catania, Italy.
  • Reddavid CM; Division of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco," Catania, Italy.
  • Strazzieri O; Division of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco," Catania, Italy.
  • Motta SC; Division of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco," Catania, Italy.
  • Frittitta V; Division of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco," Catania, Italy.
  • Dipietro E; Division of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco," Catania, Italy.
  • Comis A; Division of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco," Catania, Italy.
  • Melfa C; Division of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco," Catania, Italy.
  • Cal M; Division of Cardiology, A.O.U. Policlinico "G. Rodolico-San Marco," Catania, Italy.
  • Thiele H; Heart Center Leipzig at University of Leipzig and Leipzig Heart Science, Leipzig, Germany.
  • Webb JG; Centre for Heart Valve Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
  • Søndergaard L; The Heart Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Am J Cardiol ; 219: 60-70, 2024 05 15.
Article em En | MEDLINE | ID: mdl-38401656
ABSTRACT
Evidence regarding gender-related differences in response to transcatheter aortic valve implantation according to the valve type is lacking. This study aimed to evaluate the impact of gender on the treatment effect of Evolut PRO/PRO+ (PRO) or SAPIEN 3 Ultra (ULTRA) devices on clinical outcomes. The Comparative Analysis of Evolut PRO vs SAPIEN 3 Ultra Valves for Transfemoral Transcatheter Aortic Valve Implantation (OPERA-TAVI) is a multicenter, multinational registry including patients who underwent the latest-iteration PRO or ULTRA implantation. Overall, 1,174 of 1,897 patients were matched based on valve type and compared according to gender, whereas 470 men and 630 women were matched and compared according to valve type. The 30-day and 1-year outcomes were evaluated. In the PRO and ULTRA groups, men had a higher co-morbidity burden, whereas women had smaller aortic root. The 30-day (device success [DS], early safety outcome, permanent pacemaker implantation, patient-prosthesis mismatch, paravalvular regurgitation, bleedings, vascular complications, and all-cause death) and 1-year outcomes (all-cause death, stroke, and heart failure hospitalization) did not differ according to gender in both valve groups. However, the male gender decreased the likelihood of 30-day DS with ULTRA versus PRO (p for interaction = 0.047). A higher risk of 30-day permanent pacemaker implantation and 1-year stroke and a lower risk of patient-prosthesis mismatch was observed in PRO versus ULTRA, regardless of gender. In conclusion, gender did not modify the treatment effect of PRO versus ULTRA on clinical outcomes, except for 30-day DS, which was decreased in men (vs women) who received ULTRA (vs PRO).
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estenose da Valva Aórtica / Desenho de Prótese / Próteses Valvulares Cardíacas / Sistema de Registros / Substituição da Valva Aórtica Transcateter Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Am J Cardiol Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estenose da Valva Aórtica / Desenho de Prótese / Próteses Valvulares Cardíacas / Sistema de Registros / Substituição da Valva Aórtica Transcateter Limite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Am J Cardiol Ano de publicação: 2024 Tipo de documento: Article