Engineered mRNA-ribosome fusions for facile biosynthesis of selenoproteins.

Thaenert, Anna; Sevostyanova, Anastasia; Chung, Christina Z; Vargas-Rodriguez, Oscar; Melnikov, Sergey V; Söll, Dieter

Thaenert, Anna; Sevostyanova, Anastasia; Chung, Christina Z; Vargas-Rodriguez, Oscar; Melnikov, Sergey V; Söll, Dieter.

Afiliação

Thaenert A; Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06511.
Sevostyanova A; Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06511.
Chung CZ; Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06511.
Vargas-Rodriguez O; Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT 06511.
Melnikov SV; Biosciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Söll D; Biosciences Institute, Newcastle University Medical School, Newcastle upon Tyne NE2 4HH, United Kingdom.

Proc Natl Acad Sci U S A ; 121(11): e2321700121, 2024 Mar 12.

Article em En | MEDLINE | ID: mdl-38442159

Assuntos

Magnoliopsida; Selenocisteína; RNA Mensageiro/genética; RNA Ribossômico 16S; Selenoproteínas/genética; Ribossomos/genética; Códon de Terminação/genética; Escherichia coli/genética

Palavras-chave

SECIS; ribosome engineering; selenocysteine; tRNA; translation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Selenocisteína / Magnoliopsida Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2024 Tipo de documento: Article

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