Resolution of Severe Portopulmonary Hypertension With Inhaled Treprostinil and Liver Transplantation.
Tex Heart Inst J
; 51(1)2024 Mar 14.
Article
em En
| MEDLINE
| ID: mdl-38483473
ABSTRACT
Portopulmonary hypertension is a rare condition with a poor prognosis. Prompt management is essential for liver transplantation eligibility, a potentially curative option. This report presents a case of severe portopulmonary hypertension that resolved with a conservative therapeutic regimen of tadalafil, macitentan, and inhaled treprostinil, which ultimately enabled successful liver transplantation. There was no recurrence of pulmonary hypertension after transplantation, and the patient was weaned off most pulmonary arterial hypertension therapies. This case report is the first to provide evidence that inhaled treprostinil is a safe and effective alternative to continuous intravenous prostacyclins in portopulmonary hypertension.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Epoprostenol
/
Transplante de Fígado
/
Hipertensão Pulmonar
Limite:
Humans
Idioma:
En
Revista:
Tex Heart Inst J
Ano de publicação:
2024
Tipo de documento:
Article