Antenatal Administration of Extracellular Vesicles Derived From Amniotic Fluid Stem Cells Improves Lung Function in Neonatal Rats With Congenital Diaphragmatic Hernia.

Figueira, Rebeca L; Khoshgoo, Naghmeh; Doktor, Fabian; Khalaj, Kasra; Islam, Tasneem; Moheimani, Nazgol; Blundell, Matisse; Antounians, Lina; Post, Martin; Zani, Augusto

Figueira, Rebeca L; Khoshgoo, Naghmeh; Doktor, Fabian; Khalaj, Kasra; Islam, Tasneem; Moheimani, Nazgol; Blundell, Matisse; Antounians, Lina; Post, Martin; Zani, Augusto.

Afiliação

Figueira RL; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada; Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Khoshgoo N; Translational Medicine Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
Doktor F; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada; Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Khalaj K; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada; Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Islam T; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada; Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Moheimani N; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada; Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Blundell M; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada; Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Antounians L; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada; Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Post M; Translational Medicine Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada.
Zani A; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON, Canada; Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada; Department of Surgery, University of Toronto, Toronto, ON, C

J Pediatr Surg ; 59(9): 1771-1777, 2024 Sep.

Article em En | MEDLINE | ID: mdl-38519389

Assuntos

Líquido Amniótico; Animais Recém-Nascidos; Modelos Animais de Doenças; Vesículas Extracelulares; Hérnias Diafragmáticas Congênitas; Pulmão; Animais; Hérnias Diafragmáticas Congênitas/terapia; Líquido Amniótico/citologia; Ratos; Pulmão/patologia; Feminino; Gravidez; Ratos Sprague-Dawley; Terapias Fetais/métodos; Transplante de Células-Tronco/métodos; Éteres Fenílicos

Palavras-chave

Exosomes; Lung development; Pulmonary hypertension; Regenerative medicine; Respiratory distress syndrome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Modelos Animais de Doenças / Hérnias Diafragmáticas Congênitas / Vesículas Extracelulares / Líquido Amniótico / Pulmão / Animais Recém-Nascidos Limite: Animals / Pregnancy Idioma: En Revista: J Pediatr Surg Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Canadá

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