Sub-Nyquist sampling-based high-frequency photoacoustic computed tomography.
Opt Lett
; 49(7): 1648-1651, 2024 Apr 01.
Article
em En
| MEDLINE
| ID: mdl-38560827
ABSTRACT
High-frequency (greater than 30â
MHz) photoacoustic computed tomography (PACT) provides the opportunity to reveal finer details of biological tissues with high spatial resolution. To record photoacoustic signals above 30â
MHz, sampling rates higher than 60â
MHz are required according to the Nyquist sampling criterion. However, the highest sampling rates supported by existing PACT systems are typically within the range of 40-60â
MHz. Herein, we propose a novel PACT imaging method based on sub-Nyquist sampling. The results of numerical simulation, phantom experiment, and in vivo experiment demonstrate that the proposed imaging method can achieve high-frequency PACT imaging with a relatively low sampling rate. An axial resolution of 22â
µm is achieved with a 30-MHz transducer and a 41.67-MHz sampling rate. To the best of our knowledge, this is the highest axial resolution ever achieved in PACT based on a sampling rate of not greater than 60â
MHz. This work is expected to provide a practical way for high-frequency PACT imaging with limited sampling rates.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Opt Lett
Ano de publicação:
2024
Tipo de documento:
Article