KAT7 enhances the proliferation and metastasis of head and neck squamous carcinoma by promoting the acetylation level of LDHA.

Lu, Ying; Wang, Yong; Zhang, Leilei; Ma, Zhaofeng; Yu, Kaitao; Shu, Yao; Zou, Xuan; Yang, Jinjin; Liu, Xin; Wang, Chenglong; Du, Yimeng; Li, Qihong

Lu, Ying; Wang, Yong; Zhang, Leilei; Ma, Zhaofeng; Yu, Kaitao; Shu, Yao; Zou, Xuan; Yang, Jinjin; Liu, Xin; Wang, Chenglong; Du, Yimeng; Li, Qihong.

Afiliação

Lu Y; School of Stomatology, Southern Medical University, Guang Zhou, 510515, China; Department of Stomatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Wang Y; Department of Nuclear Medicine, The Fifth Medical Centre of Chinese PLA General Hospital, Beijing, 100071, China.
Zhang L; Department of Stomatology, 920th Hospital of the Joint Logistics Support Force, PLA, Kunming, 650032, China.
Ma Z; Department of Stomatology, Beijing Shunyi District Hospital, Beijing, 101300, China.
Yu K; Department of Stomatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Shu Y; Department of Stomatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Zou X; Department of Stomatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Yang J; Department of Stomatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Liu X; Department of Stomatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Wang C; Department of Stomatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China. Electronic address: 66937964@163.com.
Du Y; Department of Genetic Engineering, Beijing Institute of Biotechnology, Beijing, 100071, China. Electronic address: duyimeng1987@163.com.
Li Q; School of Stomatology, Southern Medical University, Guang Zhou, 510515, China; Department of Stomatology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China. Electronic address: drliqihong@gmail.com.

Cancer Lett ; 590: 216869, 2024 May 28.

Article em En | MEDLINE | ID: mdl-38593918

Assuntos

Proliferação de Células; Neoplasias de Cabeça e Pescoço; Histona Acetiltransferases; Carcinoma de Células Escamosas de Cabeça e Pescoço; Humanos; Animais; Neoplasias de Cabeça e Pescoço/patologia; Neoplasias de Cabeça e Pescoço/genética; Neoplasias de Cabeça e Pescoço/metabolismo; Carcinoma de Células Escamosas de Cabeça e Pescoço/patologia; Carcinoma de Células Escamosas de Cabeça e Pescoço/genética; Carcinoma de Células Escamosas de Cabeça e Pescoço/metabolismo; Acetilação; Linhagem Celular Tumoral; Histona Acetiltransferases/metabolismo; Histona Acetiltransferases/genética; Camundongos; L-Lactato Desidrogenase/metabolismo; L-Lactato Desidrogenase/genética; Lisina Acetiltransferases/metabolismo; Lisina Acetiltransferases/genética; Regulação Neoplásica da Expressão Gênica; Camundongos Nus; Efeito Warburg em Oncologia; Masculino; Feminino; Movimento Celular; Ensaios Antitumorais Modelo de Xenoenxerto; Invasividade Neoplásica; Isoenzimas/metabolismo; Isoenzimas/genética

Palavras-chave

Acetylation; Head and neck squamous carcinoma; KAT7; LDHA; Warburg effectx

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proliferação de Células / Histona Acetiltransferases / Carcinoma de Células Escamosas de Cabeça e Pescoço / Neoplasias de Cabeça e Pescoço Limite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Lett Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China

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