[Neurotrophin-associated mechanisms of delayed-onset muscle soreness: research progress and perspective].
Sheng Li Xue Bao
; 76(2): 301-308, 2024 Apr 25.
Article
em Zh
| MEDLINE
| ID: mdl-38658378
ABSTRACT
Delayed-onset muscle soreness (DOMS) is a common phenomenon that occurs following a sudden increase in exercise intensity or unfamiliar exercise, significantly affecting athletic performance and efficacy in athletes and fitness individuals. DOMS is characterized by allodynia and hyperalgesia, and their mechanisms remain unclear. Recent studies have reported that neurotrophic factors, such as nerve growth factor (NGF) and glial cell derived neurotrophic factor (GDNF), are involved in the development and maintenance of DOMS. This article provides a review of the research progress on the signaling pathways related to the involvement of NGF and GDNF in DOMS, hoping to provide novel insights into the mechanisms underlying allodynia and hyperalgesia in DOMS, as well as potential targeted treatment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fator de Crescimento Neural
/
Fator Neurotrófico Derivado de Linhagem de Célula Glial
/
Mialgia
Limite:
Animals
/
Humans
Idioma:
Zh
Revista:
Sheng Li Xue Bao
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China