Allergic contact dermatitis to salicylic acid: A case series of relevant sensitization.
Contact Dermatitis
; 91(2): 133-138, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-38686774
ABSTRACT
INTRODUCTION:
Allergic contact dermatitis (ACD) to salicylic acid (SA) is widely unreported. Furthermore, cross-reactivity between SA and other salicylates has not been reported despite well-documented in-group salicylate cross-reactivity.OBJECTIVE:
To describe our clinic's experience patch testing to SA, highlighting seven cases of relevant reactions and concomitant reactivity with other salicylates.METHODS:
Results of patch testing to 5% SA in petrolatum between 1 January 2020, and 9 February 2024, are reported. Seven cases of relevant reactions to SA are detailed.RESULTS:
A total of 489 patients (27.5%) were tested to SA, 21 of which were positive 7 doubtful (+/-), 14 weak positive (+), and no strong/extreme positive reactions. Four irritant reactions were documented. Of the 14 weak positive (+) reactions, 7 had definite or probable clinical relevance, 5 of which also reacted to other salicylates.CONCLUSIONS:
ACD to SA is likely underreported due to a lack of testing. In our experience, testing SA 5% petrolatum is tolerable without significant irritation. Cross-reactivity between SA and other salicylates is probable. Though SA appears to be the primary sensitizer in some cases, more studies are needed to understand its possible role as a marker for salicylate allergy.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Testes do Emplastro
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Dermatite Alérgica de Contato
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Ácido Salicílico
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Reações Cruzadas
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Contact Dermatitis
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos