New Insights into IGF-1 Signaling in the Heart.
Physiology (Bethesda)
; 39(5): 0, 2024 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-38713091
ABSTRACT
Insulin-like growth factor-1 (IGF-1) signaling has multiple physiological roles in cellular growth, metabolism, and aging. Myocardial hypertrophy, cell death, senescence, fibrosis, and electrical remodeling are hallmarks of various heart diseases and contribute to the progression of heart failure. This review highlights the critical role of IGF-1 and its cognate receptor in cardiac hypertrophy, aging, and remodeling.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fator de Crescimento Insulin-Like I
/
Transdução de Sinais
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Physiology (Bethesda)
Assunto da revista:
FISIOLOGIA
Ano de publicação:
2024
Tipo de documento:
Article