Long-term survival after systemic chemotherapy, chemoradiotherapy, and maintenance therapy for an older adult patient with recurrent pancreatic acinar cell carcinoma.
Clin J Gastroenterol
; 17(4): 771-775, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-38743170
ABSTRACT
Pancreatic acinar cell carcinoma (PACC) is a rare cancer with no specific treatment. The treatment and chemotherapy for PACC are selected according to pancreatic ductal adenocarcinoma (PDAC). Herein, we describe a recurrent PACC case of an older adult patient. The patient was treated with systemic chemotherapy, chemoradiotherapy, and maintenance therapy based on the pathologic germline BRCA2 variant, resulting in long-term survival. The pathogenic BRCA variant is detected more frequently in patients with PACC than in those with PDAC. The BRCA variant significantly impacts treatment selection and prognosis; therefore, early genomic analysis is recommended when treating PACC.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Pancreáticas
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Carcinoma de Células Acinares
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Quimiorradioterapia
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Recidiva Local de Neoplasia
Limite:
Aged
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Humans
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Male
Idioma:
En
Revista:
Clin J Gastroenterol
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Japão