Contact sensitization and self-reported eczema in Swedish painters with occupational exposure to isothiazolinones.
Contact Dermatitis
; 91(2): 126-132, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-38769738
ABSTRACT
BACKGROUND:
Due to an increasing occupational usage of isothiazolinone (IT)-containing preservatives, and their potential to cause skin sensitization and allergic contact dermatitis, that is, chronic disease, there is a need for more knowledge on how highly exposed workers are affected.OBJECTIVES:
The overall objective was to explore dermatological symptoms of potentially long-lasting or chronic character in Swedish painters.METHODS:
Building painters from western and southern Sweden were initially invited to perform a questionnaire on occurrence of skin symptoms. Participants with affirmative responses, and the right inclusion criteria, were further invited to patch testing with four different ITs benzisothiazolinone (BIT), methylisothiazolinone, methylchloroisothiazolinone and octylisothiazolinone.RESULTS:
There was a tendency towards higher occurrence of positive patch test reactions among the painters compared with occupationally unexposed registry patients; however, not statistically significant differences. BIT was the substance most frequently causing positive test results in both groups. The occurrence of adult-onset eczema was higher in painters than in the control group of electricians, and just shy of statistical significance concerning any of several skin locations (face/legs/arms/hands).CONCLUSION:
Building painters present with positive patch test reactions to common paint preservatives (ITs), and they report adult-onset eczema more often than do less occupationally exposed groups.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pintura
/
Conservantes Farmacêuticos
/
Tiazóis
/
Testes do Emplastro
/
Exposição Ocupacional
/
Dermatite Alérgica de Contato
/
Dermatite Ocupacional
/
Eczema
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Contact Dermatitis
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Suécia