Gold-Catalyzed Arylative Cope Rearrangement.
Angew Chem Int Ed Engl
; 63(33): e202406936, 2024 Aug 12.
Article
em En
| MEDLINE
| ID: mdl-38769939
ABSTRACT
Cope rearrangements have garnered significant attention owing to their ability to undergo structural reorganization in stereoselective manner. While substantial advances have been achieved over decades, these rearrangements remained applicable exclusively to parent 1,5-hexadienes. Herein, we disclose the gold-catalyzed arylative Cope rearrangement of 1,6-heptadienes via a cyclization-induced [3,3]-rearrangement employing ligand-enabled gold redox catalysis. Detailed mechanistic investigations including several control experiments, cross-over experiment, HRMS analysis, 31Pâ
NMR and DFT studies have been performed to underpin the mechanism.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Angew Chem Int Ed Engl
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Índia