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Influenza Virus Genomic Surveillance, Arizona, USA, 2023-2024.
Maqsood, Rabia; Smith, Matthew F; Holland, LaRinda A; Sullins, Regan A; Holland, Steven C; Tan, Michelle; Hernandez Barrera, Gabrielle M; Thomas, Alexis W; Islas, Mario; Kramer, Joanna L; Nordstrom, Lora; Mulrow, Mary; White, Michael; Murugan, Vel; Lim, Efrem S.
Afiliação
  • Maqsood R; Center for Fundamental and Applied Microbiomics, Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
  • Smith MF; Center for Fundamental and Applied Microbiomics, Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
  • Holland LA; Center for Fundamental and Applied Microbiomics, Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
  • Sullins RA; Center for Fundamental and Applied Microbiomics, Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
  • Holland SC; Center for Fundamental and Applied Microbiomics, Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
  • Tan M; Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
  • Hernandez Barrera GM; Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
  • Thomas AW; Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
  • Islas M; Arizona State University Health Services, Tempe, AZ 85281, USA.
  • Kramer JL; Division of Primary, Complex, and Adolescent Medicine, Phoenix Children's Hospital, Phoenix, AZ 85016, USA.
  • Nordstrom L; Valleywise Health Medical Center, Phoenix, AZ 85008, USA.
  • Mulrow M; Valleywise Health Medical Center, Phoenix, AZ 85008, USA.
  • White M; Valleywise Health Medical Center, Phoenix, AZ 85008, USA.
  • Murugan V; Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
  • Lim ES; Center for Fundamental and Applied Microbiomics, Biodesign Institute, Arizona State University, Tempe, AZ 85281, USA.
Viruses ; 16(5)2024 04 27.
Article em En | MEDLINE | ID: mdl-38793574
ABSTRACT
Influenza viruses are constantly evolving and are therefore monitored worldwide in the hope to reduce the burden of disease by annual updates to vaccine recommendations. We conducted genomic sequencing of 110 influenza A and 30 influenza B viruses from specimens collected between October 2023 and February 2024 in Arizona, USA. We identified mutations in the hemagglutinin (HA) antigenic sites as well as the neuraminidase (NA) gene in our samples. We also found no unique HA and NA mutations in vaccinated yet influenza-infected individuals. Real-time genomic sequencing surveillance is important to ensure influenza vaccine effectiveness.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Vírus da Influenza B / Genoma Viral / Influenza Humana / Mutação / Neuraminidase Limite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Viruses Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Vírus da Influenza B / Genoma Viral / Influenza Humana / Mutação / Neuraminidase Limite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: Viruses Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos