Localization of basement membrane components in mucous membrane pemphigoid.
J Invest Dermatol
; 84(2): 105-7, 1985 Feb.
Article
em En
| MEDLINE
| ID: mdl-3881535
ABSTRACT
We examined the distribution of laminin, type IV collagen, and fibronectin in subepithelial vesicles of oral mucous membrane pemphigoid (MMP). Indirect immunofluorescence staining of these macromolecules was performed on 10 frozen biopsy specimens of oral MMP. We found type IV collagen in the connective tissue floor and laminin in the epithelial roof of these lesions. Our results suggest that the inflammatory injury in oral MMP may disrupt the interaction of laminin with type IV collagen in the basement membrane zone.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Membrana Basal
/
Dermatopatias Vesiculobolhosas
/
Colágeno
/
Laminina
/
Penfigoide Mucomembranoso Benigno
/
Mucosa Bucal
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Invest Dermatol
Ano de publicação:
1985
Tipo de documento:
Article