Inflow Tract Development.
Adv Exp Med Biol
; 1441: 145-153, 2024.
Article
em En
| MEDLINE
| ID: mdl-38884709
ABSTRACT
The development of the inflow tract is undoubtedly one of the most complex remodeling events in the formation of the four-chambered heart. It involves the creation of two separate atrial chambers, the formation of an atrial/atrioventricular (AV) septal complex, the incorporation of the caval veins and coronary sinus into the right atrium, and the remodeling events that result in pulmonary venous return draining into the left atrium. In these processes, the atrioventricular mesenchymal complex, consisting of the major atrioventricular (AV) cushions, the mesenchymal cap on the primary atrial septum (pAS), and the dorsal mesenchymal protrusion (DMP), plays a crucial role.
Palavras-chave
AV cushion; AVSD; Atrioventricular cushion; BMP2; Bone morphogenetic protein 2; Coronary sinus; Dorsal mesenchymal protrusion; Dorsal mesocardium; FHF; First heart field; Islet1; Left atrium; Mesenchymal cap; Nkx2-5; OFT; Ostium primum; Outflow tract; PFO; Patent foramen ovale; Pulmonary vein; Pulmonary venous return; SHF; Second heart field; Septum primum; Septum secundum; Sinus venosus; TGFb2; Transforming growth factor-ß 2; Venous pole
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Átrios do Coração
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Adv Exp Med Biol
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos