The Leishmania ribosome: more than passive mRNA translating machinery.

ABSTRACT

While the central dogma of molecular biology describes how genetic information flows, gene expression is also affected by epigenetic and epitranscriptomic processes. A recent report by Rajan et al. demonstrates how pseudouridylation of a Leishmania ribosomal rRNA affects the expression of particular proteins an example of epitranslatomic control.